Non-Alcoholic Steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD). It is a liver condition where excess fat buildup causes inflammation and liver cell damage in individuals who drink little or no alcohol.
The contributing factors are obesity, diabetes, and high cholesterol. NASH can progress quietly, causing liver scarring and potentially liver failure if ignored or left untreated. If you are in Lucknow, ensure early detection by scheduling a visit to liver disease specialists for NASH. Follow all the instructions given by the doctor.
It can be associated with multiple conditions; however, it is most common among people who are obese and/or have Type 2 diabetes.
The following are the main characteristics:
1.Build-up of excessive fat in the liver.
2.Inflammation of the liver, called hepatitis.
3.Over time, the scarring from NASH may become severe and permanent, leading to cirrhosis.
4.It is not due to heavy alcohol consumption.
Yes, with early care and treatment, NASH can be reversible. However, if it progresses to severe damage such as cirrhosis, it may no longer be reversible.
NASH specialists in Lucknow, like Dr. Abhishek Yadav, after proper diagnosis, can curate a comprehensive treatment for the best results.
Your doctor in Lucknow can order the following diagnostic tests to offer the best NASH treatment.
Based on the results from these tests, the following comprehensive treatment in Lucknow can be recommended to you.
Weight loss through adopting a Mediterranean-style diet (which emphasizes plant-based foods and healthy fats) and exercise decreases liver fat and inflammation. This can help improve insulin sensitivity and decrease fat buildup in the liver.
Note: Even 7% to 10% weight loss shows significant benefits in the recovery process.
Insulin sensitizers such as pioglitazone can be a primary treatment for NASH, especially in those with prediabetes or type 2 diabetes. These improve the body’s ability to use insulin, decreasing blood sugar and liver fat accumulation.
Vitamin E is generally recommended as the first-line therapy for non-diabetic adults with biopsy-proven NASH, at a dose of 800 IU/day. It acts as an antioxidant to help reduce oxidative stress and liver cell damage because of fat accumulation.
Obeticholic acid shows promise for treating NASH. It works by activating the FXR, a nuclear receptor in the liver that regulates bile acids and lowers fat synthesis in the liver, lowering inflammation and progression of fibrosis.
NASH specialists in Lucknow can recommend anti-inflammatory agents to target immune cells and inflammatory signals. This helps decrease liver inflammation and prevent further liver damage.
These medicines work by activating the thyroid hormone receptor-beta. This helps improve liver metabolism and lowers the harmful fat buildup, causing liver damage.
Note: Rezdiffra (resmetirom) is the first FDA-approved drug particularly for NASH with liver scarring (fibrosis).
Omega-3 polyunsaturated fatty acids (ω-3 PUFA) have been considered a potential treatment for NAFLD and NASH because of their ability to improve lipid metabolism. They exhibit anti-inflammatory effects, reducing the risk of insulin resistance
Help in liver cell repair and decrease inflammation by supporting numerous biochemical processes, including methylation processes crucial for normal liver function.
These medicines help block inflammasome activation to reduce liver inflammation and fibrosis.
These are in their early stage. Results from studies suggest that inhibition of BET proteins may present a novel therapeutic opportunity in the therapy of NASH and liver fibrosis.
The cost of NASH Treatment in Lucknow depends on various factors like
1.Type and stage of the disease
2.Chosen treatment method (such as lifestyle changes, medications, or liver transplant)
3.The expertise of the liver specialist
4.Healthcare facility reputation
Here is the breakdown of the cost:
A healthy liver performs over 500 essential functions important for health, including flushing out harmful substances, producing bile for fat digestion, regulating blood sugar, supporting the immune system, and helping blood clot. Hence, keeping it healthy is your responsibility. Watch for NASH symptoms such as fatigue, abdominal pain, jaundice, itching, swelling, and easy bruising, and seek timely, comprehensive NASH treatment in Lucknow to avoid serious liver damage.
Looking for Best NASH treatment in Lucknow? Contact Liver Surgery India at +91 9670971552.
Kanpur - Lucknow Rd, Sector B,
Bargawan, LDA Colony, Lucknow,
Uttar Pradesh 226012
